Blue Wire

Democratic · South Carolina

Annie Andrews

U.S. Senator-elect from South Carolina

Annie Andrews, a pediatrician, is South Carolina's Democratic U.S. Senator-elect. She defeated appointed Republican Sen. Darline Graham 51.1% to 46.7% on Nov. 3, 2026 (AP data via NBC News, 99% in), the first Democratic Senate win in the state since 1998.

2026 race
U.S. Senate, South Carolina
Result
Won (flip): Andrews 51.1%, Graham 46.7% [Source]

Biography

Andrews, 45, was a pediatric hospitalist and professor of pediatrics at the Medical University of South Carolina and the 2022 Democratic nominee in SC-1. She was running against Sen. Lindsey Graham until his death in July 2026; his sister Darline Graham was appointed to the seat. Andrews campaigned on health care access, affordability and fighting corruption, CBS News reported. She is the first woman elected to the Senate from South Carolina.

Positions

  • Health care access
  • Affordability
  • Fighting corruption in Washington

Record

  • Professor of pediatrics, Medical University of South Carolina
  • 2022 Democratic nominee, SC-1

Life & background

Things you might not know, from public records.

  • She worked for 14 years as a pediatric hospitalist at MUSC Children's Hospital in Charleston. [Source]

Coverage